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Radiant Manifold in 2x4 Wall?

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Can a radiant manifold be fit into a 2x4 wall? Google's AI says it can be done with a low profile manifold, but didn't point to a suitable manifold or examples of this type of installation - possibly because I wasn't using the correct search terms on Google or here.

I have a logical central location where a manifold to feed five or six loops could be placed within the wall, but the wall is 2x4 construction. The wall is only 7 feet wide and I could fur it out to 2X6, but replacing or modifying a door frame for 2X6 probably makes that more trouble than it is worth. Loops are 1/2" PEX and leaders and loops will come from a (very low) crawl space. It's not a load bearing wall.

Thanks for any suggestions or photos.

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